Article
Metabolomic approaches to phenotype characterization and applications to complex diseases.
Expert review of molecular diagnostics - 1 Jul 2006
Oresic Matej, Vidal-Puig Antonio, Hänninen Virve
Abstract excerpt
Metabolites are the key regulators of systems homeostasis. As such, concentration changes of specific groups of metabolites may reflect systemic responses to environmental, therapeutic or genetic interventions. Thus, the study of metabolites is a powerful tool for the characterization of complex phenotypes as well as for the development of biomarkers for specific physiological responses. Therefore, metabolomics...
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