Metabolomics as a Functional Genomic Tool for Understanding Lipid Dysfunction in Diabetes, Obesity and Related Disorders

Abstract excerpt

With the rise of systems biology, a number of approaches have been developed to globally profile a tier of organization in a cell, tissue or organism. Metabolomics is an approach that attempts to profile all the metabolites in a biological matrix. One of the major challenges of this approach, as with other 'omic' technologies, is that the metabolome is context-dependent and will vary with pathology, developmental...

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