Article
Targeting the complex interactions between microbiota, host epithelial and immune cells in inflammatory bowel disease.
Pharmacological research - 1 Nov 2016
Hirata Yoshihiro, Ihara Sozaburo, Koike Kazuhiko
Abstract excerpt
Inflammatory bowel disease (IBD) is a chronic inflammatory intestinal disorder that includes two distinct disease categories: ulcerative colitis and Crohn's disease. Epidemiological, genetic, and experimental studies have revealed many important aspects of IBD. Genetic susceptibility, inappropriate immune responses, environmental changes, and intestinal microbiota are all associated with the development of IBD....
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