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Article

Acute myeloid leukemia with MYC rearrangement and JAK2 V617F mutation.

Cancer genetics - 1 Nov 2015

Ohanian Maro, Bueso-Ramos Carlos, Ok Chi Young, Lin Pei, Patel Keyur, Alattar Mona Lisa, Khoury Joseph D, Rozovski Uri, Estrov Zeev, Huh Yang O, Cortes Jorge, Abruzzo Lynne V

Abstract excerpt

Little is known about MYC dysregulation in myeloid malignancies, and the authors were unable to find published studies that evaluated MYC protein expression in primary cases of myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). Herein, we describe the clinical, morphologic, immunophenotypic, cytogenetic, and molecular genetic findings in two MDS/AML cases that contained both MYC rearrangement and the...

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Source

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Identifiers

PMID: 26382622
DOI: 10.1016/j.cancergen.2015.06.004
PMCID: PMC4835801

Genes

MYC
JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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