Article
A case of myeloid sarcoma with correlation to JAK2V617F mutation, complicated by myelofibrosis and secondary acute myeloid leukemia.
Internal medicine (Tokyo, Japan) - 1 Jan 2011
Yoshiki Yumiko, Asai Takashi, Ichikawa Motoshi, Hangaishi Akira, Ota Satoshi, Imai Yoichi, Takahashi Tsuyoshi, Kurokawa Mineo
Abstract excerpt
The activating mutation of JAK2, V617F, has been found as a frequent mutation in myeloproliferative neoplasms (MPNs), including polycythemia vera (PV), essential thrombocytosis (ET), and primary myelofibrosis (PMF). This mutation is observed not only in MPNs, but also in chronic myelomonocytic leukemia, myelodysplastic syndrome and acute myeloid leukemia (AML). We report a case of myeloid sarcoma and...
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