Article
Ethnic genomic differences in esophageal squamous cell carcinoma: Whole-exome sequencing of Han and Kazakh populations in China.
World journal of gastroenterology - 14 Dec 2025
Wei Meng-Xia, Lei Ling-Ling, Xu Rui-Hua, Liu Yong-Xuan, Wang Ran, Han Wen-Li, Fan Zong-Min, Xiao Fan-Kai, Sheyhidin Ilyar, Ma Lei, Ku Jian-Wei, Yin Ming-Zhu, Ji Ai-Fang, Bao Qi-De, Gao She-Gan, Han Xue-Na, Li Xin-Min, Chen Pei-Nan, Zhao Xue-Ke, Song Xin, Wang Li-Dong
Abstract excerpt
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a cancer with a poor prognosis, characterized by distinct geographical distribution and family clustering. AIM: To investigate if ethnic differences (Han vs Kazakh) cause molecular variations in ESCC patients via genomic sequencing 299 samples. METHODS: Here, we sequenced samples from 299 ESCC patients collected from Henan Key Laboratory for Esophageal...
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