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Article

Simultaneous genotyping of four single nucleotide polymorphisms associated with risk factors of hemostasis disorders.

Combinatorial chemistry & high throughput screening - 1 Jan 2015

Bashmakova Eugenia E, Krasitskaya Vasilisa V, Frank Ludmila A

Abstract excerpt

Multiplex simultaneous genotyping technique was developed for four polymorphisms in genes coding for blood coagulation factors and homocysteine metabolism which are considered as thrombophilia related mutations: FV Leiden, FII G20210A, MTHFR C677T, and FVII G10976A. It is based on primer extension reaction with the following bioluminescent solid-phase microassay. At that, two dierent in bioluminescence obelin...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26377543
DOI: 10.2174/1386207318666150917100134

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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