Article
Adoptive transfer of immune cells from glaucomatous mice provokes retinal ganglion cell loss in recipients.
Acta neuropathologica communications - 15 Sept 2015
Gramlich Oliver W, Ding Qiong J, Zhu Wei, Cook Amy, Anderson Michael G, Kuehn Markus H
Abstract excerpt
INTRODUCTION: Several studies have indicated that autoimmune and neuroinflammatory processes contribute to the neurodegeneration of retinal ganglion cells in human glaucoma patients and in animal models. To test the involvement of cellular immune processes in the pathophysiology of retinal ganglion cell degeneration in vivo, we carried out adoptive transfer experiments from two independent genetic mouse models of...
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