Article
Lack of Association Between Haptoglobin Phenotype and Cystic Fibrosis Outcomes.
Lung - 1 Dec 2015
Shteinberg Michal, Rivlin Joseph, Gur Michal, Konopnicki Muriel, Stein Nili, Tunney Michael M, Elborn J Stuart, Downey Damian G, Johnston Elinor, Shalom Hadar, Levy Andrew
Abstract excerpt
Haptoglobin (Hp), a heme-Iron chelator, has different isoforms which are associated with variable tendency toward infections: Hp 1-1, Hp 2-1, and Hp 2-2. Cystic fibrosis (CF) outcomes are variable and influenced by genetic and environmental factors. The aim of this study was to determine whether Hp phenotype influenced disease severity in CF. One hundred forty-two CF patients from two centers were analyzed for...
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