Article
Haptoglobin polymorphism and infection.
Advances in clinical chemistry - 1 Jan 2010
Kasvosve Ishmael, Speeckaert Marijn M, Speeckaert Reinhart, Masukume Gwinyai, Delanghe Joris R
Abstract excerpt
The haptoglobin gene is highly polymorphic in humans with strong evidence of functionally distinct biochemical phenotypes. In all human populations, three major haptoglobin phenotypes Hp 1-1, Hp 2-1, and Hp 2-2 are present, but additional phenotypes have been identified. Haptoglobin polymorphism has important biological and clinical significance. In this review, we examine the putative role of haptoglobin...
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