Article
Urine proteome analysis in Dent's disease shows high selective changes potentially involved in chronic renal damage.
Journal of proteomics - 1 Jan 2016
Santucci Laura, Candiano Giovanni, Anglani Franca, Bruschi Maurizio, Tosetto Enrica, Cremasco Daniela, Murer Luisa, D'Ambrosio Chiara, Scaloni Andrea, Petretto Andrea, Caridi Gianluca, Rossi Roberta, Bonanni Alice, Ghiggeri Gian Marco
Abstract excerpt
Definition of the urinary protein composition would represent a potential tool for diagnosis in many clinical conditions. The use of new proteomic technologies allows detection of genetic and post-trasductional variants that increase sensitivity of the approach but complicates comparison within a heterogeneous patient population. Overall, this limits research of urinary biomarkers. Studying monogenic diseases are...
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