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Article

Combination genetic signature stratifies lower-grade gliomas better than histological grade.

Oncotarget - 28 Aug 2015

Chan Aden Ka-Yin, Yao Yu, Zhang Zhenyu, Shi Zhifeng, Chen Liang, Chung Nellie Yuk-Fei, Liu Joseph Shu-Ming, Li Kay Ka-Wai, Chan Danny Tat-Ming, Poon Wai Sang, Wang Ying, Zhou Liangfu, Ng Ho-Keung

Abstract excerpt

We studied if combination genetic signature potentially stratifies lower-grade gliomas better than histology by investigating 214 lower-grade gliomas for IDH1/2 and TERTp mutations, 1p/19q codeletion and EGFR amplification as to their impact on prognostication. Prognostic association of grading was independent of other prognostic variables including age, histological type, IDH1/2, 1p/19q and TERTp status. No...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26369702
DOI: 10.18632/oncotarget.4928
PMCID: PMC4673237

Genes

IDH1
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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