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Article

Genetic diversity within the botulinum neurotoxin-producing bacteria and their neurotoxins.

Toxicon : official journal of the International Society on Toxinology - 1 Dec 2015

Hill K K, Xie G, Foley B T, Smith T J

Abstract excerpt

The recent availability of multiple Clostridium botulinum genomic sequences has initiated a new genomics era that strengthens our understanding of the bacterial species that produce botulinum neurotoxins (BoNTs). Analysis of the genomes has reinforced the historical Group I-VI designations and provided evidence that the bont genes can be located within the chromosome, phage or plasmids. The sequences provide the...

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PMID: 26368006
DOI: 10.1016/j.toxicon.2015.09.011

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