Article
Comparative genomic analyses reveal broad diversity in botulinum-toxin-producing Clostridia.
BMC genomics - 3 Mar 2016
Williamson Charles H D, Sahl Jason W, Smith Theresa J, Xie Gary, Foley Brian T, Smith Leonard A, Fernández Rafael A, Lindström Miia, Korkeala Hannu, Keim Paul, Foster Jeffrey, Hill Karen
Abstract excerpt
BACKGROUND: Clostridium botulinum is a diverse group of bacteria characterized by the production of botulinum neurotoxin. Botulinum neurotoxins are classified into serotypes (BoNT/A-G), which are produced by six species/Groups of Clostridia, but the genetic background of the bacteria remains poorly understood. The purpose of this study was to use comparative genomics to provide insights into the genetic diversity...
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