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Article

New insights into the pathogenesis of giant cell arteritis and hopes for the clinic.

Expert review of clinical immunology - 1 Jan 2016

Carmona F David, Martín Javier, González-Gay Miguel A

Abstract excerpt

Giant cell arteritis is a complex immune-mediated disease that involves large blood vessels in individuals older than 50 years. Recent studies have confirmed a strong association of this form of vasculitis with the HLA region, particularly with HLA class II genes. However, other non-HLA loci, such as protein tyrosine phosphatase non-receptor type 22, may also account for the susceptibility to giant cell...

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Biomarkers
Genetic Predisposition to Disease
Giant Cell Arteritis
HLA Antigens
Molecular Targeted Therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Protein Tyrosine Phosphatase, Non-Receptor Type 22

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PMID: 26367100
DOI: 10.1586/1744666X.2016.1089173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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