Article
WASP: allele-specific software for robust molecular quantitative trait locus discovery.
Nature methods - 1 Nov 2015
van de Geijn Bryce, McVicker Graham, Gilad Yoav, Pritchard Jonathan K
Abstract excerpt
Allele-specific sequencing reads provide a powerful signal for identifying molecular quantitative trait loci (QTLs), but they are challenging to analyze and are prone to technical artifacts. Here we describe WASP, a suite of tools for unbiased allele-specific read mapping and discovery of molecular QTLs. Using simulated reads, RNA-seq reads and chromatin immunoprecipitation sequencing (ChIP-seq) reads, we...
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