Back to search

Article

Ornaments for Accurate and Efficient Allele-Specific Expression Estimation with Bias Correction

2023-10-29

Abstract excerpt

Allele-specific expression has been used to elucidate various biological mechanisms, such as genomic imprinting and gene expression variation caused by genetic changes in cis -regulatory elements. However, existing methods for obtaining allele-specific expression from RNA-seq reads do not adequately and efficiently remove various biases, such as reference bias, where reads containing the alternative allele do not...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
28b6c575-c4cc-5ba4-b230-752d163da364
DOI
10.1101/2023.10.25.564046
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Ornaments for Accurate and Efficient Allele-Specific Expression Estimation with Bias CorrectionDOI 10.1101/2023.10.25.564046
Select a neighboring publication to make it the new centre.