Article
The Conserved G-Protein Coupled Receptor FSHR-1 Regulates Protective Host Responses to Infection and Oxidative Stress.
PloS one - 1 Jan 2015
Miller Elizabeth V, Grandi Leah N, Giannini Jennifer A, Robinson Joseph D, Powell Jennifer R
Abstract excerpt
The innate immune system's ability to sense an infection is critical so that it can rapidly respond if pathogenic microorganisms threaten the host, but otherwise maintain a quiescent baseline state to avoid causing damage to the host or to commensal microorganisms. One important mechanism for discriminating between pathogenic and non-pathogenic bacteria is the recognition of cellular damage caused by a pathogen...
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