Article
Accuracy of genotype imputation based on random and selected reference sets in purebred and crossbred sheep populations and its effect on accuracy of genomic prediction.
Genetics, selection, evolution : GSE - 22 Dec 2015
Moghaddar Nasir, Gore Klint P, Daetwyler Hans D, Hayes Ben J, van der Werf Julius H J
Abstract excerpt
BACKGROUND: The objectives of this study were to investigate the accuracy of genotype imputation from low (12k) to medium (50k Illumina-Ovine) SNP (single nucleotide polymorphism) densities in purebred and crossbred Merino sheep based on a random or selected reference set and to evaluate the impact of using imputed genotypes on accuracy of genomic prediction. METHODS: Imputation validation sets were composed of...
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