Article
CASP8 D302H and meningioma risk: an analysis of five case-control series.
Cancer letters - 18 Jan 2009
Bethke Lara, Sullivan Kate, Webb Emily, Murray Anne, Schoemaker Minouk, Auvinen Anssi, Kiuru Anne, Salminen Tiina, Johansen Christoffer, Christensen Helle Collatz, Muir Kenneth, McKinney Patricia, Hepworth Sarah, Dimitropoulou Polyxeni, Lophatananon Artitaya, Feychting Maria, Lönn Stefan, Ahlbom Anders, Malmer Beatrice, Henriksson Roger, Swerdlow Anthony, Houlston Richard
Abstract excerpt
Caspase 8 (CASP8) is a key regulator of apoptosis or programmed cell death, and hence a defence against cancer. The CASP8 polymorphism D302H has recently been shown to influence the risk of breast cancer. We tested the hypothesis that the CASP8 polymorphism D302H may influence risk of meningioma...
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