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Novel WT1 Missense Mutations in Han Chinese Women with Premature Ovarian Failure.

Scientific reports - 11 Sept 2015

Wang Huidan, Li Guangyu, Zhang Jun, Gao Fei, Li Weiping, Qin Yingying, Chen Zi-Jiang

Abstract excerpt

Premature ovarian failure (POF) is a heterogeneous disease. Though dozens of candidate genes have been identified for the genetic etiology of POF, it is largely unexplained in majority of patients. Recently, Wt1(+/R394W) mice was found to present POF-like phenotype, which indicates that WT1 might be a plausible candidate gene for non-syndromic POF. The coding region of WT1 gene was screened in 384 patients with...

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Source

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Identifiers

PMID: 26358501
DOI: 10.1038/srep13983
PMCID: PMC4566091

Genes

AMH
CDH1
FSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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