Article
Association analysis between HFM1 variation and primary ovarian insufficiency in Chinese women.
Clinical genetics - 1 May 2016
Pu D, Wang C, Cao J, Shen Y, Jiang H, Liu J, Wu B L, Zhang W, Wu J
Abstract excerpt
HFM1 is a meiosis-specific gene and expressed in germ-line tissues. More recently, evidence has indicated that variations in HFM1 gene could be causative for primary ovarian insufficiency (POI), also known as premature ovarian failure. The aim of this study was to investigate the association between HFM1 gene variants and sporadic POI in Chinese women. A total of 138 POI patients and 316 healthy controls (matched...
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