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Article

Experimental study of the protective effects of SYVN1 against diabetic retinopathy.

Scientific reports - 11 Sept 2015

Yang Shuo, He Heng, Ma Qi Si, Zhang Yong, Zhu Ying, Wan Xing, Wang Feng Wen, Wang Shuai Shuai, Liu Lei, Li Bin

Abstract excerpt

Genetic factors play an important role in the pathogenesis of diabetic retinopathy (DR). While many studies have focused on genes that increase susceptibility to DR, herein, we aimed to explore genes that confer DR resistance. Previously, we identified Hmg CoA reductase degradation protein 1 (SYVN1) as a putative DR protective gene via gene expression analysis. Transgenic mice overexpressing SYVN1 and wild-type...

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Source

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Identifiers

PMID: 26358086
DOI: 10.1038/srep14036
PMCID: PMC4642554

Genes

SYVN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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