Article
Endoplasmic reticulum stress-related factors protect against diabetic retinopathy.
Experimental diabetes research - 1 Jan 2012
Hu Wei-Kun, Liu Rong, Pei Han, Li Bin
Abstract excerpt
The endoplasmic reticulum (ER) is a principal mediator of signal transduction in the cell, and disruption of its normal function (a mechanism known as ER stress) has been associated with the pathogenesis of several diseases. ER stress has been demonstrated to contribute to onset and progression of diabetic retinopathy (DR) by induction of multiple inflammatory signaling pathways. Recent studies have begun to...
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