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Article

Clinicopathologic and genomic features of gliosarcomas.

Journal of neuro-oncology - 1 May 2012

Lee Dakeun, Kang So Young, Suh Yeon-Lim, Jeong Ji Yun, Lee Jung-Il, Nam Do-Hyun

Abstract excerpt

Gliosarcoma is a variant of glioblastoma (GBM) with both glial and mesenchymal differentiation. The genetic profile of gliosarcoma is similar to that of primary GBM, except for rare EGFR amplification. However, little is known about O6-methylguanine-DNA methyltransferase (MGMT) methylation and isocitrate dehydrogenase (IDH) 1/2 mutations in gliosarcomas. The objective of this study was to investigate the status...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22270848
DOI: 10.1007/s11060-011-0790-3

Genes

MGMT
IDH1
EGFR
IDH2

Provenance

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