Article
Primary Meningeal Pleomorphic Xanthoastrocytoma With Anaplastic Features: A Report of 2 Cases, One With BRAF(V600E) Mutation and Clinical Response to the BRAF Inhibitor Dabrafenib.
Journal of neuropathology and experimental neurology - 1 Oct 2015
Usubalieva Aisulu, Pierson Christopher R, Kavran Christina A, Huntoon Kristin, Kryvenko Oleksandr N, Mayer Theodore G, Zhao Weiqiang, Rock Jack, Ammirati Mario, Puduvalli Vinay K, Lehman Norman L
Abstract excerpt
Primary meningeal gliomas are rare tumors composed of a heterogeneous group of neoplasms. We present 2 clinically aggressive cases of primary meningeal pleomorphic xanthoastrocytoma that clinically mimicked meningioma. One case presented in the posterior fossa of a 56-year-old woman; the other centered on the left operculum of a 35-year-old woman. These cases showed many of the classic features of pleomorphic...
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