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Article

A Rare Case of BRAF-mutated Metastatic Pleomorphic Xanthoastrocytoma Patient who Developed Radiodermatitis After Receiving Anti-BRAF Treatment.

Journal of pediatric hematology/oncology - 1 Nov 2023

Atahan Ceren, Arslantas Esra, Ersen Danyeli Ayca, Celik Levent, Bozkurt Gokhan, Ugurluer Gamze, Corapcioglu Funda Vesile, Ozyar Enis

Abstract excerpt

Pleomorphic xanthoastrocytoma (PXA) is a rare type of grade 2 or 3 brain tumor that usually occurs in children and young adults. The standard treatment for PXA is maximally safe resection, usually with adjuvant radiation therapy, for high-grade tumors. BRAF V600E mutation is one of the most common molecular alterations in these tumors, with nearly 70% of cases carrying this mutation. Although BRAF inhibitors have...

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PMID: 37700448
DOI: 10.1097/MPH.0000000000002754

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