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Alzheimer's Disease: Genomics and Beyond.

International review of neurobiology - 1 Jan 2015

Song Fuhai, Han Guangchun, Bai Zhouxian, Peng Xing, Wang Jiajia, Lei Hongxing

Abstract excerpt

Alzheimer's disease (AD) is a major form of senile dementia. Despite the critical roles of Aβ and tau in AD pathology, drugs targeting Aβ or tau have so far reached limited success. The advent of genomic technologies has made it possible to gain a more complete picture regarding the molecular network underlying the disease progression which may lead to discoveries of novel treatment targets. In this review, we...

Topics

Alzheimer Disease
Genetic Association Studies
Genetic Predisposition to Disease
Genome
Genomics
Humans
Transcriptome

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 26315760
DOI: 10.1016/bs.irn.2015.05.001

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