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Article

Analysis of the Association between Catechol-O-Methyltransferase Val158Met and Male Sexual Orientation.

The journal of sexual medicine - 1 Sept 2015

Yu Wei, Tu Dan, Hong Fuchang, Wang Jing, Liu Xiaoli, Cai Yumao, Xu Ruiwei, Zhao Guanglu, Wang Feng, Pan Hong, Wu Shinan, Feng Tiejian, Wang Binbin

Abstract excerpt

INTRODUCTION: Male sexual orientation is thought to have a genetic component. However, previous studies have failed to generate positive results from among candidate genes. Catechol-O-methyltransferase (COMT), located on chromosome 22, has six exons, spans 27 kb, and encodes a protein of 271 amino acids. COMT has an important role in regulating the embryonic levels of catecholamine neurotransmitters (such as...

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Source

Identifiers

PMID: 26346727
DOI: 10.1111/jsm.12978

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of the Association between Catechol-O-Methyltransferase Val158Met and Male Sexual Orientation.PMID 26346727Read ↗

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