Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

cFinder: definition and quantification of multiple haplotypes in a mixed sample.

BMC research notes - 7 Sept 2015

Niklas Norbert, Hafenscher Julia, Barna Agnes, Wiesinger Karin, Pröll Johannes, Dreiseitl Stephan, Preuner-Stix Sandra, Valent Peter, Lion Thomas, Gabriel Christian

Abstract excerpt

BACKGROUND: Next-generation sequencing allows for determining the genetic composition of a mixed sample. For instance, when performing resistance testing for BCR-ABL1 it is necessary to identify clones and define compound mutations; together with an exact quantification this may complement diagnosis and therapy decisions with additional information. Moreover, that applies not only to oncological issues but also...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Computational Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Haplotypes

Share to Reproducibility of Results

Share to Sequence Alignment

Share to Sequence Analysis, DNA

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 26346608
DOI: 10.1186/s13104-015-1382-7
PMCID: PMC4562109

Genes

ABL1
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

cFinder: definition and quantification of multiple haplotypes in a mixed sample.PMID 26346608Read ↗

AmpSeqR: an R package for amplicon deep sequencing data analysisSemantic proximity Read ↗

AmpSeqR: an R package for amplicon deep sequencing data analysisSemantic proximity Read ↗

ShoRAH: estimating the genetic diversity of a mixed sample from next-generation sequencing data.Semantic proximity Read ↗

Long Range PCR-based deep sequencing for haplotype determination in mixed HCMV infectionsSemantic proximity Read ↗

DEMINERS enables clinical metagenomics and comparative transcriptomic analysis by increasing throughput and accuracy of nanopore direct RNA sequencingSemantic proximity Read ↗

PBHoover and CigarRoller: a method for confident haploid variant calling on Pacific Biosciences data and its application to heterogeneous population analysisSemantic proximity Read ↗

Mutant-bin: unsupervised haplotype estimation of viral population diversity without reference genome.Semantic proximity Read ↗

Deconvolution of multiple infections in Plasmodium falciparum from high throughput sequencing dataSemantic proximity Read ↗

PHARE: a bioinformatics pipeline for compositional profiling of multiclonal Plasmodium falciparum infections from long-read Nanopore sequencing data.Semantic proximity Read ↗

Long Range PCR-based deep sequencing for haplotype determination in mixed HCMV infectionsSemantic proximity Read ↗

BBmix: a Bayesian beta-binomial mixture model for accurate genotyping from RNA-sequencing.Semantic proximity Read ↗

DNA Sudoku--harnessing high-throughput sequencing for multiplexed specimen analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.