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Article

Effects of abnormal optineurin expression on the survival of the rat retinal ganglion cell line RGC-5.

Genetics and molecular research : GMR - 7 Aug 2015

Xu Z R, Jiang F G, Chen F

Abstract excerpt

The OPTN gene is thought to be associated with certain types of glaucoma and the function of the protein for which it encodes, optineurin, has been extensively researched, but with contradictory results. We explored the effects of abnormal optineurin expression on the survival of the rat retinal ganglion cell line RGC-5. Plasmids expressing wild-type (WT) or E50K mutant optineurin, or OPTN-specific double-hairpin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26345850
DOI: 10.4238/2015.August.7.27

Genes

OPTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of abnormal optineurin expression on the survival of the rat retinal ganglion cell line RGC-5.PMID 26345850Read ↗

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