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Osteopontin in Immune-mediated Diseases

4 Sept 2015

Abstract excerpt

Since its initial identification as one of the genes most highly upregulated upon T-cell activation, osteopontin (or Eta-1, as it was designated then) has been demonstrated to have many roles in the regulation of the immune response on multiple levels. It contributes to the development of immune-mediated and inflammatory diseases, and it regulates the host response to infection. In some cases, the mechanisms of...

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PMID: 26341976
DOI: 10.1177/0022034515605270

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