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Article

Clinicopathological Significance of CDKN2A Promoter Hypermethylation Frequency with Pancreatic Cancer.

Scientific reports - 4 Sept 2015

Tang Bo, Li Yang, Qi Guangying, Yuan Shengguang, Wang Zhenran, Yu Shuiping, Li Bo, He Songqing

Abstract excerpt

The prognosis of pancreatic cancer patients is very poor, with a 5-year survival of less than 6%. Previous studies demonstrated that the loss of function of CDKN2A is mainly caused by the hypermethylation of CDKN2A gene promoter; however, whether or not it is associated with the incidence of pancreatic cancer still remains unclear. In this study, we systematically reviewed the association between CDKN2A promoter...

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Identifiers

PMID: 26338139
DOI: 10.1038/srep13563
PMCID: PMC4642558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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