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Article

Characterizing DNA methylation patterns in pancreatic cancer genome

22 Apr 2009

Abstract excerpt

We performed a global methylation profiling assay on 1505 CpG sites across 807 genes to characterize DNA methylation patterns in pancreatic cancer genome. We found 289 CpG sites that were differentially methylated in normal pancreas, pancreatic tumors and cancer cell lines. We identified 23 and 35 candidate genes that are regulated by hypermethylation and hypomethylation in pancreatic cancer, respectively. We...

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PMID: 19497796
DOI: 10.1016/j.molonc.2009.03.004

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