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Epigenetic Landscape of DNA Methylation in Pancreatic Ductal Adenocarcinoma

3 Nov 2024

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, characterized by its aggressive progression and dismal prognosis. Advances in epigenetic profiling, specifically DNA methylation analysis, have significantly deepened our understanding of PDAC pathogenesis. This review synthesizes findings from recent genome-wide DNA methylation studies, which have delineated a complex DNA...

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PMID: 39584964
DOI: 10.3390/epigenomes8040041

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