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Article

Direct assessment of possible mutations in the 23S rRNA gene encoding macrolide resistance in Chlamydia trachomatis.

PloS one - 1 Jan 2022

van Niekerk J M, van Loo I H M, Lucchesi M, Morré S A, Hoebe C J P A, Dukers-Muijrers N H T M, Wolffs P F G

Abstract excerpt

Reports of potential treatment failure have raised particular concerns regarding the efficacy of the single dose azithromycin regimen in the treatment of urogenital and anorectal Chlamydia trachomatis (CT) infections. Several factors have been suggested, including heterotypic resistance. Antimicrobial susceptibility testing in CT requires cell culture with serial dilutions of antibiotics, which is laborious and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35536784
DOI: 10.1371/journal.pone.0265229
PMCID: PMC9089867

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Direct assessment of possible mutations in the 23S rRNA gene encoding macrolide resistance in Chlamydia trachomatis.PMID 35536784Read ↗

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