Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High performance methylated DNA markers for detection of colon adenocarcinoma

1 Dec 2021

Abstract excerpt

BACKGROUND: Colon cancer (CC) is treatable if detected in its early stages. Improved CC detection assays that are highly sensitive, specific, and available at point of care are needed. In this study, we systematically selected and tested methylated markers that demonstrate high sensitivity and specificity for detection of CC in tissue and circulating cell-free DNA. METHODS: Hierarchical analysis of 22 candidate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Cancer Screening and Detection
Share to Epigenetics and DNA Methylation
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34903270
DOI: 10.1186/s13148-021-01206-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High performance methylated DNA markers for detection of colon adenocarcinomaPMID 34903270Read ↗

Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer—a clinical biomarker discovery and validation studySemantic proximity Read ↗

Genome-Scale Discovery of DNA-Methylation Biomarkers for Blood-Based Detection of Colorectal CancerSemantic proximity Read ↗

DNA methylation biomarkers in colorectal cancer: Clinical applications for precision medicineSemantic proximity Read ↗

Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of DiseaseSemantic proximity Read ↗

Discovery and validation of methylation signatures in blood-based circulating tumor cell-free DNA in early detection of colorectal carcinoma: a case–control studySemantic proximity Read ↗

DNA Methylation Patterns as Noninvasive Biomarkers and Targets of Epigenetic Therapies in Colorectal CancerSemantic proximity Read ↗

Methylated circulating tumor DNA as a biomarker for colorectal cancer diagnosis, prognosis, and predictionSemantic proximity Read ↗

Efficacy of cell-free DNA methylation-based blood test for colorectal cancer screening in high-risk population: a prospective cohort studySemantic proximity Read ↗

Identification of methylation biomarkers in colorectal carcinoma and their detection in circulating tumour cellsSemantic proximity Read ↗

Quantification method of ctDNA using cell-free DNA methylation profile for noninvasive screening and monitoring of colon cancerSemantic proximity Read ↗

Hypermethylated DNA, a circulating biomarker for colorectal cancer detectionSemantic proximity Read ↗

Evaluation of a plasma cell-free DNA methylation test for colorectal cancer diagnosis: a multicenter clinical studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.