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Article

Sirtuin/uncoupling protein gene variants and carotid plaque area and morphology.

International journal of stroke : official journal of the International Stroke Society - 1 Dec 2015

Dong Chuanhui, Della-Morte David, Cabral Digna, Wang Liyong, Blanton Susan H, Seemant Chaturvedi, Sacco Ralph L, Rundek Tatjana

Abstract excerpt

BACKGROUND: Sirtuins and uncoupling proteins have been implicated in cardiovascular diseases by controlling oxidative stress. AIMS: We sought to investigate the association of sirtuins and uncoupling proteins single nucleotide polymorphisms with total carotid plaque area and morphology measured by ultrasonographic gray scale median. METHODS: We analyzed 1356 stroke-free subjects (60% women, mean age = 68 ± 9...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26332421
DOI: 10.1111/ijs.12623
PMCID: PMC6561468

Genes

SIRT6
UCP1
SIRT3
UCP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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