Article
Prediction and measurement of an autoregulatory genetic module.
Proceedings of the National Academy of Sciences of the United States of America - 24 Jun 2003
Isaacs Farren J, Hasty Jeff, Cantor Charles R, Collins J J
Abstract excerpt
The deduction of phenotypic cellular responses from the structure and behavior of complex gene regulatory networks is one of the defining challenges of systems biology. This goal will require a quantitative understanding of the modular components that constitute such networks. We pursued an integrated approach, combining theory and experiment, to analyze and describe the dynamics of an isolated genetic module, an...
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