Article
Variable exon usage of differentially-expressed genes associated with resistance of sheep to Teladorsagia circumcincta.
Veterinary parasitology - 15 Sept 2015
Wilkie Hazel, Xu Siyang, Gossner Anton, Hopkins John
Abstract excerpt
The resistance and susceptibility of sheep to the common abomasal nematode parasite, Teladorsagia circumcincta is strongly associated with the differential polarization of the immune response. Resistant animals control larval colonization by the production of a protective antibody response regulated by Th2 T cells. Susceptible sheep respond to infection by developing an inflammatory Th1/Th17 response that fails...
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