Article
Transcriptional profiling of the ovine abomasal lymph node reveals a role for timing of the immune response in gastrointestinal nematode resistance.
Veterinary parasitology - 15 Jul 2016
McRae Kathryn M, Good Barbara, Hanrahan James P, McCabe Matthew S, Cormican Paul, Sweeney Torres, O'Connell Mary J, Keane Orla M
Abstract excerpt
Gastrointestinal nematodes are a serious cause of morbidity and mortality in grazing ruminants. The major ovine defence mechanism is acquired immunity, with protective immunity developing over time in response to infection. Nematode resistance varies both within and between breeds and is moderately heritable. A detailed understanding of the genes and mechanisms involved in protective immunity, and the factors...
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