Article
Splice variants and regulatory networks associated with host resistance to the intestinal worm Cooperia oncophora in cattle.
Veterinary parasitology - 30 Jul 2015
Li Robert W, Wu Sitao, Li Cong-Jun, Li Weizhong, Schroeder Steven G
Abstract excerpt
To elucidate the molecular mechanism of host resistance, we characterized the jejunal transcriptome of Angus cattle selected for parasite resistance for over 20 years in response to infection caused by the intestinal worm Cooperia oncophora. The transcript abundance of 56 genes, such as that of mucin 12 (MUC12) and intestinal alkaline phosphatase (ALPI), was significantly higher in resistant cattle. Novel...
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