Article
Functionally distinct T-helper cell phenotypes predict resistance to different types of parasites in a wild mammal.
Scientific reports - 24 Feb 2022
Corripio-Miyar Yolanda, Hayward Adam, Lemon Hannah, Sweeny Amy R, Bal Xavier, Kenyon Fiona, Pilkington Jill G, Pemberton Josephine M, Nussey Daniel H, McNeilly Tom N
Abstract excerpt
The adaptive immune system is critical to an effective response to infection in vertebrates, with T-helper (Th) cells pivotal in orchestrating these responses. In natural populations where co-infections are the norm, different Th responses are likely to play an important role in maintaining host health and fitness, a relationship which remains poorly understood in wild animals. In this study, we characterised...
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