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Article

Reduced rate of copy number aberrations in mucinous colorectal carcinoma.

Oncotarget - 22 Sept 2015

Hugen Niek, Simmer Femke, Mekenkamp Leonie J M, Koopman Miriam, van den Broek Evert, de Wilt Johannes H W, Punt Cornelis J A, Ylstra Bauke, Meijer Gerrit A, Nagtegaal Iris D

Abstract excerpt

BACKGROUND: Mucinous carcinoma (MC) is found in 10%-15% of colorectal cancer (CRC) patients. It differs from the common adenocarcinoma (AC) in histopathological appearance and clinical behavior. METHODS: Genome-wide DNA copy number and survival data from MC and AC primary CRC samples from patients from two phase III trials (CAIRO and CAIRO2) was compared. Chromosomal copy number data from The Cancer Genome Atlas...

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Identifiers

PMID: 26329972
DOI: 10.18632/oncotarget.4706
PMCID: PMC4694861

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