Article
Polymorphism in microRNA-binding site in HNF1B influences the susceptibility of type 2 diabetes mellitus: a population based case-control study.
BMC medical genetics - 2 Sept 2015
Goda Naoki, Murase Haruna, Kasezawa Nobuhiko, Goda Toshinao, Yamakawa-Kobayashi Kimiko
Abstract excerpt
BACKGROUND: Recent genome-wide association studies (GWAS) have identified many SNPs associated with type 2 diabetes mellitus (T2DM). However, the functional roles for most of the SNPs have not been elucidated. MicroRNAs (miRNAs) are key regulators of gene expression involved in the development an...
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