Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transport proteins NHA1 and NHA2 are essential for survival, but have distinct transport modalities.

Proceedings of the National Academy of Sciences of the United States of America - 15 Sept 2015

Chintapalli Venkateswara R, Kato Akira, Henderson Louise, Hirata Taku, Woods Debra J, Overend Gayle, Davies Shireen A, Romero Michael F, Dow Julian A T

Abstract excerpt

The cation/proton antiporter (CPA) family includes the well-known sodium/proton exchanger (NHE; SLC9A) family of Na(+)/H(+) exchangers, and the more recently discovered and less well understood CPA2s (SLC9B), found widely in living organisms. In Drosophila, as in humans, they are represented by two genes, Nha1 (Slc9b1) and Nha2 (Slc9b2), which are enriched and functionally significant in renal tubules. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Epithelium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockdown Techniques

Share to Homeostasis

Share to Hydrogen-Ion Concentration

Share to Oocytes

Share to Sodium-Hydrogen Exchangers

Share to Xenopus laevis

Source

Open in PubMed Open full text

Identifiers

PMID: 26324901
DOI: 10.1073/pnas.1508031112
PMCID: PMC4577160

Genes

CPA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transport proteins NHA1 and NHA2 are essential for survival, but have distinct transport modalities.PMID 26324901Read ↗

A human Na+/H+ antiporter sharing evolutionary origins with bacterial NhaA may be a candidate gene for essential hypertension.Semantic proximity Read ↗

Diversity of the mammalian sodium/proton exchanger SLC9 gene family.Semantic proximity Read ↗

Characterization of the ion transport activity of the budding yeast Na+/H+ antiporter, Nha1p, using isolated secretory vesicles.Semantic proximity Read ↗

SLC9 Gene Family: Function, Expression, and RegulationSemantic proximity Read ↗

Endosomal Na+ (K+)/H+ exchanger Nhx1/Vps44 functions independently and downstream of multivesicular body formation.Semantic proximity Read ↗

Molecular physiology and genetics of Na+-independent SLC4 anion exchangersSemantic proximity Read ↗

Functional conservation between yeast and plant endosomal Na(+)/H(+) antiporters.Semantic proximity Read ↗

Calcineurin homologous proteins regulate the membrane localization and activity of sodium/proton exchangers in C. elegans.Semantic proximity Read ↗

The Candida albicans antiporter gene CNH1 has a role in Na+ and H+ transport, salt tolerance, and morphogenesis.Semantic proximity Read ↗

Structurally and functionally conserved domains in the diverse hydrophilic carboxy-terminal halves of various yeast and fungal Na+/H+ antiporters (Nha1p).Semantic proximity Read ↗

Heterologous expression of mammalian Na/H antiporters in Saccharomyces cerevisiae.Semantic proximity Read ↗

A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.