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Article

Identification and replication of a combined epigenetic and genetic biomarker predicting suicide and suicidal behaviors.

The American journal of psychiatry - 1 Dec 2014

Guintivano Jerry, Brown Tori, Newcomer Alison, Jones Marcus, Cox Olivia, Maher Brion S, Eaton William W, Payne Jennifer L, Wilcox Holly C, Kaminsky Zachary A

Abstract excerpt

Considerable research suggests that suicide involves effects of genes, the environment, and their interaction. Analysis of three independent data sets of post-mortem brains revealed signs of increased methylation in one particular gene, SKA2, a finding that was extended to peripheral blood samples from other cohorts of prospectively followed individuals.

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Identifiers

PMID: 25073599
DOI: 10.1176/appi.ajp.2014.14010008
PMCID: PMC7081376

Genes

SKA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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