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Article

Genetic and epigenetic analysis of plasma glial fibrillary acidic protein (GFAP) levels in PTSD.

Molecular psychiatry - 1 Jan 2026

Miller Mark W, Zhao Xiang, Wolf Erika J, Milberg William P, Fortier Catherine B, Logue Mark W

Abstract excerpt

Glial fibrillary acidic protein (GFAP) is an astrocytic marker that can be assessed in blood using single molecule array technology. Recent studies suggest that individuals with posttraumatic stress disorder (PTSD) have suppressed circulating levels of this CNS biomarker. This study examined the hypothesis that PTSD and plasma GFAP levels share common genetic and epigenetic pathways. Using data from 1096 veterans...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40931166
DOI: 10.1038/s41380-025-03232-5
PMCID: PMC12478205

Genes

GFAP
NFIA
NPSR1
PRKN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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