Article
GSTA1 gene variation associated with gestational hypertension and its involvement in pregnancy-related pathogenic conditions.
European journal of obstetrics, gynecology, and reproductive biology - 1 Nov 2015
Iorio Andrea, Spinelli Marina, Polimanti Renato, Lorenzi Federica, Valensise Herbert, Manfellotto Dario, Fuciarelli Maria
Abstract excerpt
OBJECTIVE(S): Glutathione S-transferases (GSTs) are the main phase II enzymes involved in the cellular detoxification. Through phase I and phase II detoxification reactions, the cell is able to detoxify endogenous and exogenous toxic compounds. In this study, we focused our attention on the GSTA1*-69C/T gene polymorphism (rs3957357) in order to explore its involvement in the genetic predisposition to gestational...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
