Article
Hypermutator Salmonella Heidelberg induces an early cell death in epithelial cells.
Veterinary microbiology - 22 Oct 2015
Le Gall-David Sandrine, Zenbaa Neila, Bouchard Damien, Lavault Marie-Thérèse, Bonnaure-Mallet Martine, Jolivet-Gougeon Anne, Bousarghin Latifa
Abstract excerpt
We have previously described that a strain of Salmonella Heidelberg with a hypermutator phenotype, B182, adhered strongly to HeLa cells. In this work, we showed that this hypermutator Salmonella strain invaded HeLa epithelial cells and induced cytoskeleton alteration. Those changes lead to HeLa cell death which was characteristic of apoptosis. For the first time, we showed that this hypermutator strain induced...
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